BYSTOLIC is a prescription medicine that belongs to a group of medicines called “beta blockers.” Beta blockers are thought to work by slowing the heart rate and reducing how hard the heart has to work.

BYSTOLIC has been prescribed to more than a million adults with high blood pressure. BYSTOLIC has been studied across multiple clinical trials. BYSTOLIC was shown to provide blood pressure reductions when it was used alone or when it was taken with certain other blood pressure-lowering medications.

Why Might Your Doctor Prescribe BYSTOLIC for You?

  • BYSTOLIC may help reduce high blood pressure. Lowering blood pressure can help reduce the risk of a future stroke or heart attack.
  • BYSTOLIC was shown to provide blood pressure reductions when it was used alone or when it was taken with certain other blood pressure-lowering medications. Tell your doctor about any medications you are taking or planning to take, including, but not limited to, antiarrhythmics, antidepressants, other beta blockers, digitalis, or calcium channel blockers, and discuss the potential for interactions.
  • BYSTOLIC has a low incidence of side effects. Please click the image below for the most common side effects experienced by patients taking BYSTOLIC in clinical studies.
  • Discontinuation rate due to side effects from those same studies was 2.8% of patients taking BYSTOLIC versus 2.2% of those on placebo.
  • BYSTOLIC offers once-daily dosing. BYSTOLIC can be taken with or without food.

Adequate blood pressure control may require more than one kind of high blood pressure medication. In fact, many people with high blood pressure take 2 or more medications.

In addition to beta blockers such as BYSTOLIC, some treatment options may include other types of high blood pressure medications, such as diuretics, angiotensin-converting enzyme inhibitors (ACEIs), angiotensin II receptor blockers (ARBs), and calcium channel blockers (CCBs).

BYSTOLIC was shown to provide additional blood pressure reductions when it was added to certain other blood pressure-lowering medicines. BYSTOLIC should not be used in combination with another beta blocker. Certain CCBs have been known to interact with beta blockers, so people taking these medications (such as diltiazem and verapamil) with BYSTOLIC should be monitored by their doctors. Ask your doctor for additional information about combining medications.

If you have or are being treated for a condition related to either your kidneys (renal impairment) or liver (hepatic impairment), tell your doctor before taking BYSTOLIC.

Discuss your treatment options with your doctor if you have coronary artery disease or angina. Do not stop taking BYSTOLIC suddenly. You could have chest pain or a heart attack. If your doctor decides that you should stop taking BYSTOLIC, he or she will lower your dose slowly and over time.

Let your doctor know immediately if you notice any changes in how you are feeling while on BYSTOLIC.

What should I tell my healthcare provider before taking BYSTOLIC?

Before starting BYSTOLIC, tell your healthcare provider about all of your medical conditions, including if you:

  • Have asthma or other lung problems (such as bronchitis or emphysema)
  • Have problems with blood flow in your feet and legs (peripheral vascular disease). BYSTOLIC can make symptoms of blood flow problems worse.
  • Have diabetes and take medicine to control blood sugar
  • Have thyroid problems
  • Have liver or kidney problems
  • Have had allergic reactions to medications or have allergies
  • Have a condition called pheochromocytoma (rare adrenal gland tumor)
  • Are pregnant or trying to become pregnant. It is not known if BYSTOLIC is safe for your unborn baby. Talk with your doctor about the best way to treat your high blood pressure while you are pregnant.
  • Are breastfeeding. It is not known if BYSTOLIC passes into your breast milk. You should not breastfeed while using BYSTOLIC.
  • Are scheduled for surgery and will be given anesthetic agents
  • Have had acute angina (symptoms include chest pain or discomfort) or an MI (heart attack) as BYSTOLIC has not been studied in patients with these conditions

Also, to avoid a potentially serious or life-threatening condition, tell your healthcare provider if you are taking or plan to take any prescription or over-the-counter medications, vitamins, or herbal products, including:

  • Certain CYP2D6 inhibitors (such as some antiarrhythmics like quinidine or propafenone or certain antidepressants such as fluoxetine or paroxetine, etc)
  • Other beta blockers
  • Digitalis
  • Certain calcium channel blockers (such as verapamil and diltiazem)
  • Antiarrhythmic agents (such as disopyramide)

Next: How BYSTOLIC Works

FAQs about high
blood pressure
Answers to common questions about high blood pressure and how BYSTOLIC may help.
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10th Anniversary Bystolic!

2018 marks BYSTOLIC’s 10-year anniversary.
BYSTOLIC has been prescribed to over 3.2
million adults with high blood pressure.

BYS113199 02/18